Searchable abstracts of presentations at key conferences in endocrinology

ea0099p605 | Late-Breaking | ECE2024

Title: investigating molecular mimicry between SARS-CoV-2 antigens and pancreatic islet antigens in type 1 diabetes pathogenesis using near-sequence similarity

Beltazar Emmanuel , Beltazar Edoardo , Siddique Owais , Patel Tayyibah , Panchal Honey , Sivakumar Pravenaa

Background: Type 1 diabetes mellitus (T1DM) involves the autoimmune destruction of pancreatic islet beta cells, with recent research implicating a role for viral infections in its onset. The rise in T1D cases during the COVID-19 pandemic has sparked investigations into potential causes. Molecular mimicry between SARS-CoV-2 antigens and pancreatic islet antigens has been suggested as a plausible mechanism, yet no attempts have been made to explore this phenomenon as comparing f...